DAB10-HPLC 80%-99%
Silybin (silibinin) is the major flavonolignan from the extracts of milk thistle seed, Silybum marianum. The whole extract, known as silymarin, has been found to protect the liver from both acute and chronic toxicity and injury. Silybin blocks the production of superoxide in PMA-activated rat Kupffer cells with an EC50 of around 100 μM.1 Silybin also blocks the synthesis of leukotriene B4 by these same cells with an IC50 of about 15 μM. Thus, part of the protective effects of silybin could be due to 5-lipoxygenase inhibition.
Silibinin, also known as silybin, is the major active constituent of silymarin, the mixture of flavonolignans extracted from blessed milk thistle (Silybum marianum) consisting of silibinin A and B, isosibilinin A and B, silicristin, silidianin. Both in vitro and animal research suggest that silibinin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins.[1][2] Silibinin has also demonstrated anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent and -independent human breast carcinoma cells, human ectocervical carcinoma cells, human colon cancer cells, and both small and nonsmall human lung carcinoma cells.
Please contact Mr. Joe King. by silymarin-silybin at hotmail com.
We are selling silybin silibinin with DAB10 HPLC 80%-99% pure grade.
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China (Mainland)
